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In the Advanced tab, you can find default settings used by all zones.
The settings contained in the Multimedia section have features that you can adjust to protect against some potential vulnerabilities. For instance, attackers may be able to track your usage or exploit the software you use to play multimedia data.
CERT/CC recommends disabling the options to play sounds and videos by unchecking these boxes.
Under the Programs tab, you can specify your default applications for viewing Web sites, e-mails, and other network related tasks.
You can also prevent Internet Explorer from showing you a message asking to be your default Web browser.