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Another revamped feature in iOS 5 is notifications. The new Notification Center in iOS 5 gives you a greater overview of what’s happening, but that comes at the cost of greater battery consumption.
Settings > Notifications
My advice here is two-fold. First, disable notification for any apps that you don’t care about by clicking on the individual apps and switching off Notification Center.
Second, control which apps are visible on the Lock Screen by switching off View in Lock Screen … the more you have showing, the more often your screen will flick into life, draining precious battery power.