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Work for a smaller company
If you're unwilling to leave the field of IT entirely, you could step down from that FTSE 100 position and join a much smaller company.
Having a smaller network to deal with, far fewer computers, and users who don't have that same attitude towards you will remove the weight of the world from your shoulders.
You could even step into the voluntary sector and really feel wanted and valued. Although not-for-profit organisations have their own set of headaches, they aren't nearly as intense as those you experience in the upper echelons of capitalism.