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The first thing you'll notice with the new Google Plus look is there's now a left hand Google Plus application ribbon. The idea is to make it easier for you to get to the parts of Google Plus you hang out the most in.
For more about the new Google Plus, read my blog.
On a large display though, you'll also see there's a large white space between the update stream and your IM/VoIP/video-conference panel. Something, we don't know what yet, is going to go there. Video? Your choice of gadgets ala iGoogle, we don't know.