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On the System/Processor tab, make sure you enable PAE/NX. And, if, and only if, you have a system with multiple core or processors, you can add another CPU to Windows 8. In my case with a six-core Intel Core i7, I gave Windows 7 two CPUs.
Under the System/Acceleration tab make certain that both Enable VT-X and AMD-V and Enable Nested Paging are checked.
Windows 8 wants all the graphics power you can give it. To do this, first enable both 3D and 2D video acceleration. This, in turn, will let you give Windows 8 up to 256MBs of video RAM, instead of the default maximum of 128MBs. Go ahead and up your video memory to 256. You'll be glad you did.