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The first step is to ruthlessly eliminate unwanted tiles from the Start screen.
Right-click each tile you want to remove so that it shows a checkmark in the upper right corder, as I've done here. (If you accidentally select a tile that you want to keep, just right-click again to clear the checkmark.)
When you've selected the fill list, click Unpin from Start in the App bar along the bottom. The selected tiles are removed from the Start screen. The programs themselves remain available for use.