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Niall's comments strike a very strong chord with my thoughts...speaking very well to the subject that E2.0 is comprised of many things, especially new approaches to methods and very importantly new tools. What seems so important to me is keeping in mind that how people choose to work and inter-act is the basis for productivity - the tools (software, communications technology, etc.) just support that. Sharing intrinsic or tacit knowledge, as one example as Niall mentioned, is a process, how a company chooses to implement that process - through which tools and methodology - is where E2.0 can come into play with great benefit.
There is a tendency to have great fear of change by some, as well as a tendency to over-actively embrace change by others. Between these extreme arcs of the pendulum lies rational consideration of what works and has benefit, and what is a passing - or very importantly - a transitional phase or product. Radical embracement or dismissal of E2.0 serves no-one; open discussion and study does.