Actually you can run Node.js in Windows using Cygwin, so a full Linux VM is not required. @Smarx already has a chat program running in Azure:
Slides: http://cdn.blog.smarx.com/mixslides/index.html#15
Demo: http://chat.smarx.com
Code: https://github.com/smarx/smarxchat
That said, a native port would be awesome!
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