At a ceremony held in central London last night and attended by politicians and celebrities from all walks of life, Berners-Lee claimed the top gong among a list of 2004 award winners which included double gold-medal winning Olympian Dame Kelly Holmes and architect Sir Norman Foster.
Berners-Lee received the award in the science category before also walking away with the overall award and a cheque for £25,000.
Collecting his gong at the Royal Courts of Justice he said: "I have won awards for computers but I have never won an award for being British."
In June 2004 Berners-Lee received a €1m award from the Finnish Technology Award Foundation, having previously resisted any temptation to cash in on his invention, fearing it would have stifled development.
Although in recent years Berners-Lee has been based at the Massachusetts Institute of Technology in the US he expressed pride in being British.
"I am very proud to be British, it is great fun to be British and this award is just an amazing honour," he said.
In 2002 Berners-Lee also made it onto the BBC's shortlist for the greatest ever Britons -- an award eventually won by Winston Churchill.