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While the iPhone's screen isn't the most fragile around – some feel like they're made of cheese – Apple needs to get beyond the need for its devices to need screen protectors to prevent scratches.
If the rumor that Apple is planning to use sapphire displays is true, then screen scratches should be a thing of the past.
About the only time I connect the cable to my iPhone is when it's charging, and given the frankly pathetic battery life, this is something I'm doing a lot.
Please Apple, add wireless charging to the iPhone. This would be so cool, and open up the way for awesome accessories such as an in-car charging cradle where I wouldn’t have to futz about plugging in the cable each time I use it.
More robust construction
Along with a tougher screen, I'd like to see Apple make the whole iPhone a lot more robust. A number of companies are making their smartphones waterproof and dustproof, and this is certainly something that would appeal to users, especially considering how common a problem water damage is.