AMD's top-end, 3.4 GHz (4.0 GHz turbo), 16-core/32-thread is a behemoth.

• 16 cores / 32 threads
• 3.4 GHz base and 4.0 GHz precision boost clocks
• Socket sTR4
• DDR4 Support
• 8MB L2/32MB L3 cache
• 14nm Summit Ridge
• Support for 64 PCIe lanes
• Unlocked for overclocking

Price: $999

The ASUS ROG Zenith Extreme sTR4 features the X399 chipset, and comes with support for 128GB of RAM, and the following expansion:

• Extended ATX Form Factor
• AMD X399 Chipset
• AMD TR4 Socket
• 8 x DDR4-3200 (OC)
• 6 x SATA III, 3 x M.2, 1 x U.2
• 4 x PCIe 3.0 x16 Slots
• 1 x PCIe 2.0 x4 & 1 x PCIe 2.0 x1 Slots
• SupremeFX S1220 8-Channel HD Audio
• 802.11ac Wi-Fi & Bluetooth 4.1
• Nvidia SLI & AMD CrossFireX Support

Price: $550

Why 64-gigabyte? Why not!

• DDR4 2133 (PC4 17000)
• Timing 13-15-15-28
• CAS Latency 13
• Voltage 1.2V

Price: $570

A super-fast SSD to put your operating system and other applications you want to load fast onto.

• M.2 2280
• 512GB
• PCI-Express 3.0 x4
• Max sequential reads: Up to 3500 MBps
• Max sequential writes: Up to 2100 MBps

Price: $299

A secondary drive for your data, applications and other general storage needs.

• Interface: SATA 6.0Gb/s
• Capacity: 2TB
• RPM: 7200 RPM
• Cache: 64MB
• Improved Architectural Designs: Dual Core Processor, High Resolution Controller (HRC), StableTrac Technology
• Improved Data Protection: Vibration Control Technology (VCT), Corruption Protection Technology (CPT), NoTouch Ramp Load Technology
• Superior responsiveness with the next-generation speed that you need

Price: $125

This 1000W PSU offer plenty of overhead for overclocking and adding more components such as an additional GPU or more drives.

• ATX12V / EPS12V
• Full Modular
• 80 PLUS GOLD Certified
• 100 - 240 V 47 - 63 Hz
• +3.3V@25A, +5V@25A, +12V@83.3A, -12V@0.8A, +5VSB@3A

Price: $140

Does everything you could ever want from an optical drive.

• Extreme 16X Blu-Ray writing speed
• M-disc Support
• BDXL Support

Price: $85

What case you get is a very personal choice (and if this is something you're going to be looking at and working with for the next few years, it's sometimes worth investing in).

Personally, I like a case that is robust (flimsy cases are a pain), aren't filled with sharp metal shards that will rip at my flesh, and offer plenty of space for hardware.

• Steel/Plastic/Tempered Glass ATX Mid Tower
• 2 x USB 3.0/Mic/Headphone front ports
• 6 x 3.5-inch/2.5-inch internal 3.5-inch drive bays

Price: $90