I'm pretty partial to my nüvi GPS receiver from Garmin because I've always preferred the nüvi's maps and user interface design to that of their competition. One thing that's a boon for Mac owners is Garmin's beta Project Bobcat software for Mac OS X that was announced in January and was recently updated to version 184.108.40.206 in July.
Typically, GPS receivers require that you peck out your destination address on the built-in touchscreen on the device. While fine for occasional use the touchscreen isn't exactly efficient when it comes to entering long addresses or multiple waypoints. A much faster way to get waypoints into your nüvi is to use their Project Bobcat software for Mac OS X.
Bobcat makes your life much easier by allowing you to transfer waypoints, tracks, and routes between your Mac and your Garmin device, manage your data using your Garmin maps, search for points of interest from the convenience of your Mac then sync them to your GPS receiver. Bobcat is also excellent for removing erroneous and duplicate entries in your Favorites list and for fixing waypoint typos that you never get around to.
Bobcat is another great reason for Mac owners to love the nüvi.
What's your preferred automotive GPS receiver these days? Why?