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Here's the whole reason for buying this backpack design -- the TSA approved laptop compartment. As you can see, you can fold it out in a "butterfly" fashion separate from the rest of the backpack, which can have its other compartments closed and zipped up while your bag goes through the scanner. The laptop is secured in a pouch with a Velcro strap, so it won't fall out during the scanning process. However, other than magazines and a few papers underneath I wouldn't store anything else in this section.
Here is the part of the laptop compartment that butterflies opposite of the laptop pouch. As you can see here, this section is completely flush and has no way to store anything else against this. I'd like to see Mobile Edge add a large zippered pouch area or perhaps two zippered pouches where other items can be stored, as there is still a lot of room left in here when this compartment is closed. I found myself able to shove baseball caps and a spare change of clothing as well as sandwiches and other stuff here when dragging the pack around during the week.
The ScanFast backpack also has a convenient zipper compartment on the side with an expandable netting where you can store a large water bottle or other beverage.