The companies launched a new platform that combines the Microsoft Azure Pack with networking devices and servers from Cisco's ACI.
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Terms of the deal were not disclosed, but the transaction is expected to close in the next few weeks.
The company, which offers e-signature and digital transaction management services, continues to benefit from the shift to remote work and social distancing during the COVID-19 pandemic.
The layoffs are mostly within the sales team working on SurveyMonkey for Business, a product that's failed to resonate with users.
Government Cloud has been revamped with the Lightning Experience, which combines the various components of the Lightning platform.
With this deal, the enterprise software giant has now spent roughly $1.2 billion in three business days on cloud acquisitions.
The companies are aiming to make Box a third-party repository for content stored in Google Docs, Sheets, and Slides.
The companies plan to manage and secure third-party applications by using the configurations built into iOS, a framework they said enables centralized policy management.
Box has been pursuing industry-specific certifications that would make it possible to deploy the Box platform at scale within heavily regulated industries.