I have installed from the Live CD on my Lifebook S6510, and it seems to work very well. However, I have also tried to install it on my Lifebook S2110, so far without much success. I suspect that the problem is with the driver for the ATI display adapter.
Fedora is produced with the assistance of Red Hat, and is basically a derivative of Red Hat Enterprise Linux. As such, users who already have RHEL on corporate systems, for example, might find this a very interesting option.