"When I was in college, I wanted to be involved in things that would change the world. Now I am."
"It's normal to feel fear, like, you'd have to have something mentally wrong if you didn't feel fear."
"Going from PayPal, I thought: 'Well, what are some of the other problems that are likely to most affect the future of humanity?' Not from the perspective, 'What's the best way to make money?'"
"I'm hopeful they will do things like engineering, or write books, or just, in some way, add more than they take from the world."
"The thing that's worth doing is trying to improve our understanding of the world, and gain a better appreciation of the universe, and not to worry too much about there being no meaning."
"You want to have a future where you're expecting things to be better, not one where you're expecting things to be worse."
"You want to be extra rigorous about making the best possible thing you can. Find everything that's wrong with it and fix it. Seek negative feedback, particularly from friends."
"You know, try and enjoy yourself. Because, actually, life's pretty good. It really is."
"People shouldn't think, 'I feel fear about this and therefore shouldn't do it'."
"Given that this is the first time in 4.5 billion years where it's been possible for humanity to extend life beyond Earth, it seems like we'd be wise to act while the window was open, and not count on the fact it will be open a long time."
"If something is important enough, even if the odds are against you, you should still do it."
"Really, the only thing that makes sense is to strive for greater collective enlightenment."
"We should aspire to increase the scope and scale of human consciousness in order to better understand what questions to ask."
"[Physics is] a good framework for thinking. ... Boil things down to their fundamental truths and reason up from there."
"Persistence is very important. You should not give up unless you are forced to give up."
"The first step is to establish that something is possible; then probability will occur."
"Failure is an option here. If things are not failing, you are not innovating enough."
"There's a fundamental difference, if you look into the future, between a humanity that is a space-faring civilization, that's out there exploring the stars ... compared with one where we are forever confined to Earth until some eventual extinction event."